JAK/STAT INHIBITION NORMALIZES LIPID COMPOSITION IN 3D HUMAN EPIDERMAL EQUIVALENTS CHALLENGED WITH TH2 CYTOKINES

JAK/STAT Inhibition Normalizes Lipid Composition in 3D Human Epidermal Equivalents Challenged with Th2 Cytokines

Derangement of the epidermal barrier lipids and dysregulated immune responses are key pathogenic features of atopic dermatitis (AD).The Th2-type cytokines interleukin IL-4 and IL-13 play a prominent role in AD by activating the Janus Kinase/Signal Transduction and Activator of Transcription (JAK/STAT) intracellular signaling axis.This study aimed t

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Religious Coping Styles, General Health, and Psychological Well-Being Among Mothers of Mentally Disabled Children

Objectives: The birth and presence of an exceptional child in a family can be considered as an undesirable challenging event.This event may be associated with stress, frustration, sadness, and despair.This study Heated Merchandisers/Display aimed to examine the relationship of religious coping styles with general health and psychological well-being

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Persistent environmental endocrine-disrupting chemicals in ovarian follicular fluid and in vitro fertilization treatment outcome in women

Several international organizations have recently highlighted endocrine-disrupting chemicals (EDCs) as factors of concern in human reproduction.Since successful reproduction is dependent on timely and appropriate action of hormones, disruption of the endocrine system could lead to difficulties in conceiving or carrying a pregnancy to term.EDCs are

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